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Sagar Vaidya Phones & Addresses

  • 8687 Grand Ave, Yucca Valley, CA 92284

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Us Patents

Methods For Stimulating Tlr Irf3 Pathways For Inducing Anti-Microbial, Anti-Inflammatory And Anticancer Responses

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US Patent:
20060057104, Mar 16, 2006
Filed:
Apr 24, 2003
Appl. No.:
10/512124
Inventors:
Genhong Cheng - Calabasas CA, US
Robert Modlin - Sherman Oaks CA, US
Sagar Vaidya - Yucca Valley CA, US
Sean Doyle - Los Angeles CA, US
Assignee:
THE Regents of the University of California Office of the President - Oakland CA
International Classification:
A61K 48/00
A61K 38/21
A61K 39/00
A61K 31/739
A61K 31/4745
A61K 31/337
US Classification:
424085400, 514054000, 514044000, 424185100, 514291000, 514449000
Abstract:
The present invention provides methods for stimulating Toll-like receptors (TLR) to activate IRF (e.g., an IRF3) and signaling pathway, and thereby directing an antimicrobial activity. The present invention also provides methods for identifying agents that bind and/or stimulate TLR and mediate induction of an IRF3 pathway, thereby directing an antimicrobial activity. Additionally, the invention provides methods and agents for suppressing stimulation of TLR, thereby directing an anti-inflammatory response.
Sagar A Vaidya from Yucca Valley, CA Get Report